Arc Centre of Excellence for Advanced Molecular Imaging

Display of Native Antigen on cDC1 That Have Spatial Access to Both T and B Cells Underlies Efficient Humoral Vaccination.

Yu Kato, Thiago M Steiner, Hae-Young Park, Rohan O Hitchcock, Ali Zaid, Jyh Liang Hor, Sapna Devi, Gayle M Davey, David Vremec, Kirsteen M Tullett, Peck S Tan, Fatma Ahmet, Scott N Mueller, Sylvie Alonso, David M Tarlinton, Hidde L Ploegh, Tsuneyasu Kaisho, Lynette Beattie, Jonathan H Manton, Daniel Fernandez-Ruiz

2020-10-01

Follicular dendritic cells and macrophages have been strongly implicated in presentation of native Ag to B cells. This property ha..

Comparison of Hartree-Fock and Hartree-Fock-Slater approximations for calculation of radiation damage dynamics of light and heavy atoms in the field of an x-ray free-electron laser

A Kozlov, HM Quiney

2019-07-01

Simulations of radiation damage in single-molecule imaging using an x-ray free-electron laser use atomic rates calculated in the l..

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

NA Gherardin, L Loh, L Admojo, AJ Davenport, K Richardson, A Rogers, PK Darcy, MR Jenkins, HM Prince, SJ Harrison, H Quach, DP Fairlie, K Kedzierska, J McCluskey, AP Uldrich, PJ Neeson, DS Ritchie, DI Godfrey

2018-12-01

Mucosal-associated invariant T (MAIT) cells are T cells that recognise vitamin-B derivative Ag presented by the MHC-related-protei..

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

CE Teh, N Lalaoui, R Jain, AN Policheni, M Heinlein, S Alvarez-Diaz, JM Sheridan, E Rieser, S Deuser, M Darding, HF Koay, Y Hu, F Kupresanin, LA O'Reilly, DI Godfrey, GK Smyth, P Bouillet, A Strasser, H Walczak, J Silke

2016-11-18

The linear ubiquitin chain assembly complex (LUBAC) is essential for innate immunity in mice and humans, yet its role in adaptive ..

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

NA Gherardin, AN Keller, RE Woolley, J Le Nours, DS Ritchie, PJ Neeson, RW Birkinshaw, SBG Eckle, JN Waddington, L Liu, DP Fairlie, AP Uldrich, DG Pellicci, J McCluskey, DI Godfrey, J Rossjohn

2016-01-19

A characteristic of mucosal-associated invariant T (MAIT) cells is the expression of TRAV1-2⁺ T cell receptors (TCRs) t..